ASA seems to have a number of niches. It is generally good at OLTP and can be used as a basis for a general database project. There are certainly examples of implementations supporting 100 or more users.

A major area for ASA databases is with applications that need to distribute the database with the application as a general storage area for internal components, but the database is not a major part of the deliverable. Sybase themselves have done this with the IQ meta data storage. Prior to release 11 of IQ, the meta data was stored in an ASE database. Now, with IQ 12, the meta data has moved to being stored in ASA. This makes the installation of IQ into production environments much simpler.

ASA has excellent ODBC support, which makes it very attractive to tools oriented towards ODBC.