Prokaryotic cells do not have a pre-defined nucleus. The chromosomes in prokaryotes are dispersed in the cytoplasm. In eukaryotes, the chromosomes remain intact inside the nucleus and there is a conspicuous nuclear membrane surrounding the nucleus.

Another difference is that, there is cytoplasmic movement in prokaryotes, whereas there is no cytoplasmic movement in eukaryotes.

Prokaryotic: also no membrane-covered organelles, has circular DNA and bacteria, Eukaryotic: membrane-covered organelles, linear DNA and all other cells. Prokaryotic as a group is the most metabolically diverse. Eukaryotic makes many histones, a type of protein that structurally stabilizes the DNA.