Disappointments are different from failures. It is an intelligent interviewer who asks this question; it is also an opportunity for an astute interviewee to shine. The question itself is very positive – it asks to show how you benefited. Note also that it does not give any specific details of specific disappointments, so you don’t have to open your mouth and insert your foot. Instead be general. Sum up your answer with “I treat disappointments as a learning experience, I look at what happened, why it happened and how I would do things differently in each stage should the same set of circumstances appear again. That way, I put disappointment behind me and am ready to face the new days’ problems”.