Many times freshers tend to answers such questions in the affirmative. You must remember that your first job work culture impacts your entire job life. If you opt to work in the weekends, you must never expect free time even during weekends. It is best to set a reasonable expectation in the very beginning. There is no harm in honestly stating that you do not hope to work during weekends as you wish to have sometime with your family too. A good company is sure to accept this answer in the right spirit.