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“Bio Physics frequently Asked Questions in various Bio Physics job Interviews by interviewer. Get preparation of Bio Physics job interview”



12 Bio Physics Questions And Answers

2⟩ What is the Church or Turing thesis?

Turing and Church had considered various computational

models, such as

Turing machines, random-access machines, and so on. All

these computational

models could be implemented through physical systems subject to

the laws of classical mechanics. While studying many such

computational

models, computer scientists came up with the following Holy

Grails:

1

1. Church-Turing thesis: This states that any computational

model

is as powerful as the Turing machine. In other words, given

any computational

model, we can simulate computations on that model using

the Turing machine. The simulation may of course involve a

blow-up

in time taken as well as in space used.

2. Strong Church-Turing thesis: This states that for any

computational

model, a polynomial-time algorithm for a decision problem in

that computational model can be simulated by a

polynomial-time algorithm

in the Turing machine model. In looser language, if we think

of polynomial time as the notion of tractability, then

tractability in

any computational model is equivalent to tractability in the

Turing

machine model.

3. Strong Church-Turing thesis (randomized version): This states

that for any computational model, a bounded-error

probabilistic polynomial

time algorithm for a decision problem in that computational

model can be simulated by a bounded-error probabilistic

polynomial

time algorithm for the problem in the Turing machine model.

In looser

language, if we think of BPP as the notion of tractability,

then BPP

is any computational model is equivalent to tractability in

the Turing

machine model.

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4⟩ What are the advantages and disadvantages of transgenic animals for neuroscientific studies?

the advantages are

► in medical research, transgenic animals are used to

identify the functions of specific factors in complex

homeostatic systems through over- or under-expression of a

modified gene (the inserted transgene);

► in toxicology: as responsive test animals (detection of

toxicants);

► in mammalian developmental genetics;

► in molecular biology, the analysis of the regulation of

gene expression makes use of the evaluation of a specific

genetic change at the level of the whole animal;

► in the pharmaceutical industry, targeted production of

pharmaceutical proteins, drug production and product

efficacy testing;

► in biotechnology: as producers of specific proteins;

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5⟩ What are neuromodulators?

Neuromodulators modulate regions or circuits of the brain.

They affect a group of neurons, causing a modulation of

that group.

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6⟩ What are the basic principles of regulation?

Principle for Regulation (especially of GEne expression) lies in either positive control(eukaryotes) or negative control(prokaryotes and lower eukaryotes) It depends on certain cis acting elements like promoter,enhancer,etc. and trans acting elements like repressors,transcription factors etc.

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8⟩ What is Movements?

As plants are fixed to the ground, they cannot move bodily

but their protoplasm is sensitive to certain external

factors act as stimuli such as heat, light, gravity,

chemicals, electricity etc.

Movements may be classified into two main groups.

1. Autonomic or Spontaneous.

2. Paratonic or Induced.

Spontaneous Movements. It is the movements of creation

organs of plants without the influence of any external

stimuli e.g. movement of protoplasm and cilia, brisk

movement of many desmids movement of protoplasm and cilia,

brisk movement of many desmids etc..

This type of movements may be of two kinds.

(a)Movement of variation:- These movement are due to

variation in turgity of cell. This movement is exhibited by

pulsation.

This kind of movement is seen in Indian telegraph plant.

(b)Movement of growth:- This si movement of growing regions

die to unequal growth of organs on different sides. This

kind is seen in some creepers and trailers and this type of

movement is very slow.

Induced Movement:-This is movement of plant organ are

induced by some external stimuls. These induced movements

are of following kinds

(a)taxes

(b)tropisms

(c)nasties

(a)Taxes:-Taxic movements are the movements of free organs

or entire free organism induced by external sources at

temperature light and chemical substance. Cillated bodies as

Zoospores and antherozoids show this kind of movement. These

bodies either show positive or negative movement by the

stimulus.

(b)Tropism:- In this type of movement the organ concerned

moves either towards the source of the stimulus or away from

it. These movements are also influenced by external stimulus

as contact gravity and moisture. These movements are of

following kinds according to nature of stimulus.

(c)Haptotropism:-This moment is induced by contact with

foreign body. Climbers, Tendils and twinning stems show

this kind of movement, when climbers or tendrils some in

contact with any support, the opposite side of contact

continues to grow while the growth of contacted side is

checked. This opposite side continues to grow while the

growth of contacted side is checked. This opposite side

continue to grow until it coil around the object. Some

climbers climb clockwise some move anticlockwise.

(d)Phototropism:- These movements of plant organs are due to

influence of light. Some organs of plants are attracted by

light and grow towards it as shoots. These are positively

heliotropic or positively phototropic but some orgems e.g.

roots grow away form light are known to be negatively

phototropic or negatively heliotropic. Dorsiventral leaves

are said to be Diaheliotropic these grow at tight angles

to the direction of light so their upper surface is only

exposed to light.

(e) Geotropism:-This kind of plant movement is due to

influence of forced gravity. The roots shows positive

geotropism but stem show negative geotropism.

(f)Moisture:-This movement of plant organs is due to

moisture and is known as hydrotropism. Roots show a great

tendency to grow towards the source of moisture and these

are therefore known as positively hydrotropism.

(g)Nasties or Nastic Movements:- Nasties or nastic movements

are movements dorsiventral or like petals, leaves induced by

external stimuli as contact light, and temperature. These

movements not like tropic movements, as in these directions

of movements is not determined by direction of stimulus.

Two the of movements are found under these which are as follows

(h)Scismonasty:-This type of movement is so called as this

is brought about by some mechanical stimuli as contact with

a foreign body; drops of rain etc.

Examples of plants which show this kind of movements are

sensitive plant, Neptunia

Nyctinasty:-This type of movement is due to alternation of

day and night i.e. light and darkness. Leaves are mostly

affected by this kind of movement. Lequminous plants show

this kind of movements.

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9⟩ Explain the terms MS-DOS and WINDOWS?

MS dos is a command user interface(cui )and windows is

graphical user interface (gui) means user can interact with

os only through the set of internal and external dos

commands whereas in windows it can be done by just a

clicking on items

directory in dos is caleed folder in windows

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11⟩ What is the yous of HPLC, how we use the columns, what is the important in the pharma field?

HPLC is high performance liquid chromatography,it is used

for analytical purpose for identification of impurity in

drugs during its synthesis. during preparation phase it

helps in understanding the solvent to be chosen and RT of

the component. it can also separate different component of

drug based on their Retention time. RT varies with column

used and the mobile phase used.

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12⟩ Ammeter burns out when connected in parallel. give reasons?

I don't think so. because ammeter measure current, for which resistant should be low. this is possible only when ammeter is connected in parallel order.

one case may happen if resistant is extremely low then maximum current will pass, then only there are chances of burning the ammeter.

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