Treatment of oligodendrogliomas may include the following:

Surgery, usually with radiation therapy.

A clinical trial of surgery and radiation therapy with or without chemotherapy for tumors that cannot be completely removed by surgery.

A clinical trial of chemotherapy using one or more drugs.

Treatment of anaplastic oligodendroglioma may include the following:

Surgery plus radiation therapy with or without chemotherapy.

Chemotherapy using more than one drug.

Radiation therapy with or without chemotherapy using more than one drug.

Clinical trials of new treatments.