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⟩ This year a report from India indicates that a single dose of Amphotericin B can result in the cure of Leishmania donovani rather than prolonged treatment by fairly toxic medication. If confirmed this will be a major advance in the treatment of Kala-azar. Which of the following statements is false regarding systemic Leishmaniasis?

* A. It is spread by the bite of the sand fly

* B. Macrophages ingest the organism and move about the body facilitating its spread

* C. Diagnosis can often be made by identifying amastigotes in cells aspirated from the spleen or bone marrow

* D. Untreated patients frequently recover themselves

* E. Kala-azar should be considered as one of the possibilities in someone who has lived in an endemic area and has an enlarged spleen

Correct Answer: D

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