101⟩ Creutzfeldt-Jakob disease is caused by?
* A. JC virus
* B. Pumuula virus
* C. Prions
* D. SV40 virus
Correct Answer: C
Microbiology
Home Medical Microbiology
“Microbiology Interview Questions and Answers will guide us now that Microbiology is the study of microorganisms, which are unicellular or cell-cluster microscopic organisms. This includes eukaryotes such as fungi and protists, and prokaryotes. Viruses, though not strictly classed as living organisms, are also studied. So learn more about Microbiology with the help of this Microbiology Interview Questions with Answers guide”
124 Microbiology Questions And Answers
102⟩ Rabies virus produces infection of?
* A. Astrocytes
* B. Oligodendrocytes
* C. Neurons
* D. Macrophages
Correct Answer: C
103⟩ The most frequent cause of viral meningitis in the United States is?
* A. Enteroviruses
* B. Rhabdoviruses
* C. California/Lacrosse virus
* D. Lymphocytic choriomeningitis virus
Correct Answer: A
104⟩ Common symptoms of hepatitis include?
* A. Fever, nausea, diarrhea
* B. Malaise, anorexia, jaundice
* C. Nausea, vomiting, right upper quadrant abdominal pain
* D. Clear urine, dark colored stools, anorexia
Correct Answer: B
105⟩ Hepatitis A can be transmitted by?
* A. Changing diapers on an infected baby
* B. Having sex with someone who is infected
* C. Eating cooked meat
* D. Needle sticks injuries from infected patients
Correct Answer: A
106⟩ A 30 year old patient comes in with symptoms of hepatitis. The following serological results are obtained Hepatitis A IgM antibody negative, Hepatitis A IgG antibody positive, Hepatitis B surface antigen positive, Hepatitis B surface antibody negative, Hepatitis C antibody negative. This set of results suggests that the patient has acute?
* A. Hepatitis A
* B. Hepatitis B
* C. Hepatitis C
* D. Hepatitis A and B
Correct Answer: B
107⟩ A major characteristic of hepatitis C is?
* A. It is transmitted by eating raw oysters
* B. It is highly likely to cause chronic ongoing infection
* C. Most patients have severe symptoms when first infected
* D. It is a DNA virus
Correct Answer: B
108⟩ HIV is the same as?
* A. HTLV III
* B. HTLV II
* C. HTLV I
* D. None of the above
Correct Answer: A
109⟩ The likelihood of HIV being transmitted from a pregnant woman to her infant in the absence of antiretroviral therapy is about?
* A. 1 in 500
* B. 1 to 5 %
* C. 20 to 25%
* D. 50 to 75%
Correct Answer: C
110⟩ One of the characteristics of HIV infection is that?
* A. The virus multiplies slowly with a half-life of weeks matching the slow rate of disease progression
* B. There is rapid dissemination of virus within the first few weeks of infection to all tissues
* C. In early infection the virus is most actively multiplying within the bloodstream
* D. There is little if any immune response to HIV infection, and that is why this infection is so overwhelming
Correct Answer: B
111⟩ Serologic conversion to a positive test for HIV infection occurs?
* A. In 2-3 days
* B. In 3-4 weeks
* C. In 3-6 months
* D. May take up to 10 years
Correct Answer: B
112⟩ One of the key differences between amantidine/rimantidine and the newer neuraminidase inhibitor influenza virus drugs is?
* A. drug allergy
* B. antimetabolic effect on host cells due to lack of specificity for viral enzymes
* C. rate of development of drug resistance
* D. drug-drug interactions associated with competition for cytochrome P450 enzymes
Correct Answer: C
113⟩ Which of the following best characterizes antiviral chemotherapy in comparison to bacterial chemotherapy?
* A. Few drug targets, toxicity problematic
* B. Sensitivity tests of limited value
* C. Toxicity a minor problem, multiple enzymatic targets
* D. Many more drug options are available to treat viral infections
Correct Answer: A
114⟩ HIV reverse transcriptase, a critical target in modern antiretroviral chemotherapy, performs which critical function for the virus?
* A. Cleaves polyprotein precursor leading to functional assembly of viral core
* B. Cleaves sialic acid residue from glycoprotein permitting attachment and entry into cell
* C. Transcribes RNA into DNA
* D. Activates 2', 5’ oligoadenylate synthetase
Correct Answer: C
115⟩ Foscarnet interacts with which of the following viral enzymes?
* A. Pyrophosphate-binding site of the polymerase
* B. Protease
* C. Nucleoside reductase
* D. Reverse transcriptase
Correct Answer: A
116⟩ Enteroviruses are most closely related to which of the following viruses?
* A. Herpes simplex
* B. Hepatitis C
* C. Hepatitis A
* D. Rotavirus
* E. Rubella
Correct Answer: C
117⟩ The following statements are clearly true about enteroviruses EXCEPT?
* A. There are many serotypes
* B. They can cause a variety of diseases which imitate bacterial infection
* C. They are an important cause of meningitis
* D. They are an important cause of diarrhea
Correct Answer: D
118⟩ All of the following are syndromes associated with enteroviruses EXCEPT?
* A. Conjuctivitis
* B. Coronary artery disease
* C. Myocarditis
* D. Pericarditis
* E. Pleuritis
Correct Answer: B
119⟩ Antiviral drugs currently on the market, including acyclovir and pencyclovir are active against enteroviruses?
* A. True
* B. False
Correct Answer: B
120⟩ All of the following are true statements regarding viruses EXCEPT?
* A. They contain both RNA and DNA
* B. The nucleic acid may be single or double stranded
* C. They are obligate intracellular parasites
* D. They reproduce using host cell energy
* E. The infectious particle is called a virion
Correct Answer: A
