121⟩ Give the classification of null cells.
Null cells are classified into three types.
1. Natural killer cells
2. Antibody dependant cellular cytotoxic cells
3. Lymphokine activated killer cells.
Immunology
Home Medical Immunology
“Immunology Interview Questions and Answers will guide us now that Immunology is a broad branch of biomedical science that covers the study of all aspects of the immune system in all organisms. Immunology deals with, among other things, the physiological functioning of the immune system in states of both health and disease. Learn conceptual Immunology or get preparation of Immunology jobs interview by our this Immunology Interview Questions and Answers Guide.”
200 Immunology Questions And Answers
122⟩ What are null cells?
The lymphocytes that are devoid of markers for T and B- cells are called null cells.
123⟩ What are TH- cells?
T helper cells (TH) will recognize the antigen when it is presented by antigen presenting cell along with MHC class – II complex. They secrete various cytokines activate B – cells Tc cells and a variety of cells that participate in the immune response.
124⟩ What is the life span of a plasma cell?
The life span of a plasma cell is 2 – 3 days.
125⟩ What are plasma cells?
They are antibody-secreting cells. They are oval in shape and twice the size of small lymphocytes, with a centrally placed oval nucleus containing large blocks of chromatin located peripherally.
126⟩ What is B – lymphocyte?
They are derives from bone marrow stem cells. Their development and maturation takes place in bone marrow. Matured B-cells leave the bone marrow and migrate via blood stream to the secondary lymphoid organs.
127⟩ Give the classification of lymphocytes
They are classified into two types.
T- lymphocytes: derived from thymus
B – lymphocytes: derived from bone marrow
128⟩ What are lymphocytes?
They are the central cells of immune system responsible for acquired immunity, diversity, specificity, memory, self and non-self recognition.
Lymphocytes are small, round cells found in peripheral blood, lymph, lymphoid organs and in many tissues.
129⟩ What is haematopoisis?
Formation and development of red and white blood cells from stem cell is called haematopoisis.
130⟩ What is bursa of fabricius?
It is a lympho epithelial organ arising as a pouch from the dorsal part of the cloacae in birds. Its development, structure, and function are parallel to those of thymus. In birds, it is the primary site of B-cells maturation.
131⟩ What are T- cells?
Lymphocytes produced in the thymus are called as T-cells or thymus dependant lymphocytes.
132⟩ What is the function of bone marrow?
Bane marrow serves as a site for B-cell development and maturation. Immature B-cells proliferate and differentiate within the microenvironment of the bone marrow into immuno competent of bursal lymphocyte (or) B-cell.
133⟩ What is the relation between thymus and immune function?
The importance of thymus in lymphocyte proliferation and development of cell mediated immune response came from experiments involving neonatal thymectomic in which the thymus was surgically removed from newborn mice. These thymectaomide mice showed a dramatic decrease in T-Lymphocytes and an absence of cell mediated immune response. This condition is seen in congenital birth defect in humans.
134⟩ What is the function of thymus?
The primary function of thymus is the production of thymic lymphocyte. It is the major site for lymphocyte proliferation in the body.
135⟩ What are secondary lymphoid organs?
Lymphnode, spleen, various mucosal associated lymphoid tissues (MALT) are secondary lymphoid organs. After acquiring immune competency, the lymphocytes migrate along blood and lymph streams and accumulate in the peripheral lymphoid organs.
136⟩ What are primary lymphoid organs?
Thymus and Bone marrow are the primary lymphoid organs. During haematopiosis, immature lymphocytes are generated. These become mature and acquire immune competence within primary lymphoid organs. Primary lymphoid organs are also called as central lymphoid organs.
137⟩ What is artificial passive immunity?
It is the resistance passively transferred to a recipient by administration of antibodies.
138⟩ What is natural passive immunity?
It is the resistance passively transferred from the mother to the baby. Antibodies are transferred predominantly through the placenta. By active immunization of mother during pregnancy is possible to improve the quantity of immunity.
139⟩ How Passive immunity is classified?
Passive immunity is classified into two types.
1. Natural passive immunity
2. Artificial passive immunity
140⟩ Define artificial active immunity, and give an example?
It is the resistance induced by vaccines. Vaccine is preparation of live or killed microorganisms or their products used for immunization.
Ex: 1. Bacterial vaccines- 1) Live - BCG for Tuberculosis
Killed - TAB for entire fever.
Ex: 2.Viral vaccines- 1) Live – ORAL polio militias.
Killed – SALK polio militias
